Engineered immune cells take on brain cancer in early trial
NCT ID NCT04134117
First seen Jan 10, 2026 · Last updated May 23, 2026 · Updated 16 times
Summary
This early-phase study tested a therapy called tisagenlecleucel, which uses a patient's own immune cells engineered to target cancer, in 13 people with primary central nervous system lymphoma. The main goal was to check safety, and researchers also looked at whether the treatment shrank tumors. Participants were 60 or older who could not tolerate or did not respond to standard chemotherapy.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02115, United States
Conditions
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