Engineered immune cells tackle brain cancer in early trial

NCT ID NCT04134117

First seen Jan 10, 2026 · Last updated May 15, 2026 · Updated 14 times

Summary

This early-phase study tested a personalized cell therapy called tisagenlecleucel in 13 patients with primary central nervous system lymphoma, a rare brain cancer. The main goal was to check safety, and researchers also looked at whether the treatment shrank tumors. Participants were 60 years or older who had not responded to or could not tolerate standard chemotherapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PRIMARY CNS LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.