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Could a simple pill before surgery beat back head and neck cancer?

NCT ID NCT07254962

First seen Jan 07, 2026 · Last updated Jun 18, 2026 · Updated 24 times

Summary

This study tests whether taking a short course of capecitabine pills before surgery can shrink tumors and improve outcomes for people with HPV-negative head and neck cancer. About 75 adults with stage III or IVa cancer will be randomly assigned to either standard care or capecitabine before surgery. The goal is to see if this approach reduces tumor size, makes surgery less complex, and improves cancer-free survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma laryngeal neoplasm larynx cancer Mouth Neoplasms oral cavity cancer skin cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.