Massive cancer registry aims to unlock better GI cancer care
NCT ID NCT07605702
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is a registry that collects medical information and biological samples from up to 100,000 people with gastrointestinal cancers, such as pancreatic or colorectal cancer. No new treatments or drugs are given. The goal is to gather real-world data to help researchers answer future questions, improve best practices, and connect patients to relevant clinical trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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May 2038
An estimate. End dates often move.
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This is a multicenter, retrospective and prospective study designed to build a database and a virtual biospecimen repository of patients with GI cancers.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Retrospective Cohort: 1. Must have reached the age of majority in the jurisdiction where enrolled (18 years; Alabama/Nebraska 19; Puerto Rico 21). 2. Must have histologically proven GI cancer seen at the site within the 20 years preceding activation, and are: 1. Deceased, or 2. Lost to follow-up ( \>1 year lapse in contact since last visit). Prospective Cohort: 1. Must have reached the age of majority in the jurisdiction where enrolled (18 years; Alabama/Nebraska 19; Puerto Rico 21). 2. Must have histologically proven Gastrointestinal (GI) cancer. 3. Patient or legally authorized representative capable of understanding and willing to provide signed informed consent (assent if applicable). 4. Patient/Legally Authorized Representative (LAR) agrees to collection of clinical data and information available on archival tissue and subsequent excess specimens obtained as part of standard-of-care. Exclusion Criteria: Retrospective Cohort: 1\. Cases in which patient's medical chart denotes restricted use of health information. Prospective Cohort: 1\. Prisoners will not be approached for participation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
10 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Fred Hutch
Seattle, Washington, 98109, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Mt. Sinai
New York, New York, 10029, United States
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Northwell Health
Lake Success, New York, 11042, United States
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Roswell Park Comprehensive Cancer Center
Buffalo, New York, 14203, United States
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Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland, 21287, United States
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UC San Diego Health
San Diego, California, 92093, United States
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UT Health San Antonio
San Antonio, Texas, 78229, United States
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UT Southwestern Medical Center
Dallas, Texas, 75390, United States
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Other studies related to the condition(s) this trial covers.
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- Can MRI and computer models predict how well cancer drugs reach tumors?
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- Burning the edges: a new way to stop colon polyps from coming back