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Can kicking nicotine change cannabis habits? study investigates

NCT ID NCT06239350

Knowledge-focused Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study looks at young adults aged 18 to 25 who use both tobacco/nicotine products and cannabis. Researchers want to understand what happens to cannabis use when participants try to quit nicotine. All participants receive remote counseling and incentives to stop using nicotine for 12 weeks, and their cannabis use is tracked along the way.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
counseling and contingency management
What this could lead to
If successful, this could reveal how cannabis and tobacco interact during quit attempts, potentially guiding better dual-use cessation strategies.
What could go wrong
This is an observational behavioral study, not a treatment trial. Results may not apply to all users, and quitting nicotine may not affect cannabis use as expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 350 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2024

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Between the ages of 18 and 25 years old * Must use at least one nicotine or tobacco product (nicotine vaping and/or cigarettes) on at least 20 out of the past 30 days for at least the past 3 months * Must express interest in nicotine cessation (all products) * Must submit a positive instant-read, oral fluid cotinine sample prior to enrollment * Must report use of cannabis on at least 10 out of the past 30 days * Must submit a positive instant-read cannabinoid test prior to enrollment * Must be able to provide informed consent Exclusion Criteria: * Any significant or acutely unstable medical, psychiatric, or substance use problem that would contraindicate research, interfere with safety, compromise data integrity, or preclude consistent study participation * Pregnant (self-report) or trying to become pregnant * Self-reported use of medications with smoking cessation efficacy * Immediate interest in cannabis cessation or treatment

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Conditions

The condition(s) this trial relates to.

cannabis dependence nicotine dependence Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nicotine dependence Tobacco use disorder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Medical University of South Carolina - Charleston

    RECRUITING

    Charleston, South Carolina, 29403, United States

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