High confusion: study tests THC isolates on driving skills
NCT ID NCT06236815
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study with 5 adults looked at how two cannabis compounds (delta-9-THC and delta-8-THC) affect driving ability. Participants took the compounds and then used a driving simulator and field sobriety tests. The goal was to see if it's possible to measure impairment and drug levels in the body. This was a small feasibility study, not a treatment trial.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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5 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 49 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * At least 18 years of age, no older than 49 years of age * Recent cannabis use (within past two years) * Good mental health as determined by self-reported responses to the Psychopathology Screener * Absence of any major medical, cardiovascular, endocrine, and neurological condition as determined by self-reported responses to the Medical History Screener * In possession of a valid drivers' license with at least two years of driving experience * English-speaking (able to provide consent and complete questionnaires) * Written Informed Consent Exclusion Criteria: * Any serious prior adverse response to cannabis * History of or current substance use disorder as determined by self-reported responses to the Internalizing, Externalizing, and Substance Use Disorder Screener * Pregnancy or lactation (pregnancy test, if needed) * Use of medications that may impact driving ability (e.g., mood stabilizers, sedatives)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Wisconsin
Madison, Wisconsin, 53792, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.