Massive study digs into cancer treatment failures in poorer nations
NCT ID NCT07246213
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will look back at the medical records of 18,000 children, teens, and young adults with cancer treated in five low- and middle-income countries. The goal is to measure how often treatment fails or causes serious side effects, especially for leukemia and lymphoma. No new drugs or treatments are being tested — instead, researchers hope to find patterns that can guide future efforts to improve care in places where resources are limited.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify key barriers and gaps in cancer care in low-resource settings, pointing toward practical interventions to improve survival.
- What could go wrong
- This is a retrospective chart review, not a treatment trial. It cannot prove what works, only describe what happened. Results may not apply to other regions or hospitals.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 18,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will comprise pediatric patients aged 0-21 years diagnosed with cancer, reflecting diverse demographic backgrounds and clinical characteristics.
- Ages
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0 to 21 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Subjects must meet all the following criteria to be included in this registry: 1. Participants must be willing and able to provide informed consent prior to enrollment in the registry. 1. For minors or individuals unable to provide informed consent, assent must be obtained along with consent from a legal guardian. 2. Note: Exemption applies to this criterion when waiver of informed consent/assent is granted by Institutional Review Board(IRB)/Independent Ethics Committee(IEC)/Competent Authorities(CAs). 2. A confirmed diagnosis of any type of cancer within the 15 years prior to the site's activation date. 3. Age 0 to 21 years at the time of diagnosis. 4. Received substantial anti-cancer treatment at the participating center, including but not limited to: 1. Chemotherapy 2. Surgery 3. Radiation therapy 4. Immunotherapy 5. Medical records are available and accessible for review Exclusion Criteria: * Subjects meeting any of the following criteria will be excluded from this registry: 1. Patients who only visited the participating center for: 1. Consultation without subsequent primary anti-cancer treatment at the participating center 2. Pathology, radiology, or other diagnostic evaluations without treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites in 4 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fundación Ayúdame a Vivir
NOT_YET_RECRUITINGEl Salvador, El Salvador, 1101, El Salvador
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Hospital Escuela
NOT_YET_RECRUITINGTegucigalpa, Distrito Central, 11101, Honduras
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Hospital Mario Catarino Rivas
NOT_YET_RECRUITINGSan Pedro Sula, Cortés Department, 21102, Honduras
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Unidad Nacional de Oncología Pediátrica (UNOP)
RECRUITINGGuatemala City, Guatemala
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Yeolyan Center for Cancer and Blood Disorders
RECRUITINGYerevan, Armenia
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