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Heart scan could predict breathing tube removal success

NCT ID NCT07075926

Knowledge-focused Sponsor: Kanuni Sultan Suleyman Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at whether a simple heart ultrasound can help doctors know when it's safe to remove a breathing tube from ICU patients. Researchers will measure heart function in 50 adults just before planned tube removal and then check if they can breathe on their own for 24 hours. The goal is to find a better way to predict success and avoid complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple, non-invasive tool to better decide when to remove breathing tubes, reducing complications and hospital stays.
What could go wrong
This is a small, early observational study with only 50 participants. The results may not apply to all ICU patients, and the ultrasound measurements might not reliably predict outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients admitted to the intensive care unit (ICU) who are receiving invasive mechanical ventilation and are scheduled for extubation after fulfilling standard weaning criteria. All participants will be hemodynamically stable at the time of echocardiographic assessment. Patients with significant structural heart disease, inadequate echocardiographic imaging windows, or ongoing extracorporeal support will be excluded. The population represents a typical critically ill cohort undergoing weaning from mechanical ventilation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Currently receiving mechanical ventilation in the ICU * Planned extubation after meeting standard weaning criteria * Hemodynamically stable at the time of echocardiographic evaluation * Written informed consent obtained from the patient or legally authorized representative Exclusion Criteria: * Surgery within the previous 24 hours * Presence of significant valvular heart disease or known cardiomyopathy * Inadequate acoustic window for transthoracic echocardiography * Ongoing use of extracorporeal support (e.g., ECMO) * Patients with Do-Not-Resuscitate (DNR) orders or expected to die within 24 hours * Re-intubation planned prophylactically regardless of clinical status * Pregnant patients

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Weaning failure of mechanical ventilation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital

    RECRUITING

    Istanbul, Istanbul, 34303, Turkey (Türkiye)

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