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Heart scan may predict who can breathe on their own

NCT ID NCT07073976

Knowledge-focused Sponsor: Kanuni Sultan Suleyman Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether a simple heart ultrasound can help doctors know when it's safe to remove a breathing tube from ICU patients. Researchers will measure right heart function in 60 adults just before planned tube removal, then check if they need breathing support again within 24 hours. The goal is to find a better way to predict weaning success and avoid failed extubation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple, non-invasive tool to better decide when to safely remove breathing tubes in ICU patients.
What could go wrong
This is a small, early observational study with only 60 participants. The results may not apply to all ICU patients, and the heart measurements might not reliably predict outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients who are receiving invasive mechanical ventilation in the intensive care unit (ICU) and are scheduled for planned extubation based on standard clinical weaning criteria. All participants must be hemodynamically stable and able to undergo transthoracic echocardiographic assessment prior to extubation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Receiving invasive mechanical ventilation in the ICU * Planned extubation (weaning) according to standard clinical criteria * Hemodynamically stable at the time of transthoracic echocardiography (TTE) * Ability to undergo echocardiographic assessment within 2 hours prior to extubation * Informed consent obtained from patient or legal representative Exclusion Criteria: * Known severe tricuspid valve disease or congenital heart disease * Moderate to severe pericardial effusion or cardiac tamponade * Inadequate acoustic window for transthoracic echocardiography * Patients requiring urgent or unplanned extubation * Use of extracorporeal life support (e.g., ECMO) at the time of assessment * Known pulmonary embolism or acute cor pulmonale * Pregnancy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Weaning failure of mechanical ventilation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital

    RECRUITING

    Istanbul, Istanbul, 34303, Turkey (Türkiye)

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