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Could a bacterial pill stop wheeze in babies after severe lung infection?

NCT ID NCT05064631

First seen Nov 20, 2025 · Last updated May 25, 2026 · Updated 27 times

Summary

This study tested whether giving infants an oral bacterial lysate (Broncho-Vaxom) after a severe bout of bronchiolitis could reduce their risk of developing wheezing. 173 infants who had been hospitalized for bronchiolitis received either the bacterial lysate or a placebo for up to 24 months. The goal was to see if the treatment could prevent future wheeze episodes, which are linked to asthma later in childhood.

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Contacts and locations

Locations

  • King's College Hospital NHS Foundation Trust

    London, SE5 9RS, United Kingdom

  • Royal London Hospital

    London, E1 1FR, United Kingdom

  • University Hospital Southampton NHS Foundation Trust

    Southampton, SO16 6YD, United Kingdom

Conditions

Explore the condition pages connected to this study.