Can a cream stop light from darkening your skin?
NCT ID NCT07537595
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested seven different cosmetic creams to see if they could prevent skin darkening caused by high-energy visible light (like from the sun or screens). 33 healthy adults with fair to medium skin had creams applied to their back before being exposed to a specific blue-violet light. Researchers measured skin color changes and checked for redness or irritation over 7 weeks to find out which products worked best.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
33 people
The number who actually took part.
- Started
-
Jun 2024
- Finished
-
Dec 2024
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Healthy male and female volunteers from 18 to 60 yo, with Fitzpatrick III and IV and an ITA° between 18° to 35° at screening.
- Ages
-
18 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Caucasian subjects 2. Male and female participants 3. Aged between 18 and 60 years old 4. Skin phototypes III-IV 5. Average ITA° on the back between 18° and 35° (± 2°) at screening and baseline/inclusion visit 6. Uniform skin color over the eight test zones (difference in ITA° between each zone ≤ 4°) 7. Untanned back (no UV exposure - natural or artificial - during the 2 months prior to inclusion) 8. No scar, spot, tattoo or excess hair on investigational zones 9. Subject having given written informed consent 10. Subjects able to read and understand study documents 11. Subjects with an official domicile 12. Subject covered by health insurance or social security 13. Female subjects of child-bearing potential using a safe method of contraception for at least 3 months prior to and throughout the study Exclusion Criteria: 1. Pregnant, lactating, or planning to become pregnant during the study 2. Planned UV exposure (sunlight or sunbeds) of investigational zones throughout the study 3. Sunbed use or sun exposure of investigational zones within the 3 months prior to inclusion 4. Presence of sunburn (erythema) on the back 5. Dermatological disorders affecting investigational zones (naevi, freckles, excess hair, uneven skin tone, vitiligo, photodermatological problems) 6. History of skin cancer 7. History of abnormal response to sun 8. Presence of recent suntan or photo-test marks (per investigator opinion) 9. History of allergy, hypersensitivity, or serious reaction to any cosmetic product 10. Any concomitant medical condition that may interfere with the study (per investigator opinion) 11. Use of systemic medication for more than 5 consecutive days within the month prior to inclusion (e.g., steroids, antihistamines, antibiotics, vitamin A derivatives, psoralen) 12. Use of depigmenting, whitening or propigmenting topical treatments within the 3 months prior to inclusion 13. Physical treatment including laser or phototherapy (PUVA, IPL, PDT) within the past 6 months on investigational sites 14. Planned intensive sport (\> 5 hours per week) or swimming during the study 15. Participation in another clinical study within 30 days prior to inclusion 16. Deprived of liberty by adjunction or official decision 17. Unable to be contacted by phone in case of emergency
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Healthy volunteers are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CIDP Biotechnology S.R.L
Bucharest, Romania
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New sedative candidate goes Head-to-Head with propofol in early human test
- Can a Room-Temperature dairy drink build muscle?
- New injection MWN117 tested for safety in obesity
- Can a new drug avoid the high? soticlestat put to the test
- Liver trouble changes how drugs work: scientists test soticlestat
- Can a hard cycling sprint change a Heart-Calming peptide?