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Placebo power: can a saline spray beat jump nerves?

NCT ID NCT07522437

Symptom relief Sponsor: University of Auckland, New Zealand Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether an open-label placebo nasal spray (a spray with no active ingredients, clearly labeled as a placebo) can reduce stress in 260 adults about to do a canyon swing. Participants will either use the spray or receive no treatment. Researchers will measure stress levels, how long they hesitate before jumping, and whether they choose to jump again. The goal is to see if the placebo effect works even when people know it's a placebo.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
open-label placebo nasal spray (saline solution)
What this could lead to
If it works, this could show that even knowing you're taking a placebo can help reduce stress in nerve-wracking situations.
What could go wrong
This is a small, early-stage study in a very specific setting (a canyon swing). The placebo effect is unpredictable, and results may not apply to other types of stress or to everyday life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 260 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Signed-up to complete the canyon swing * Aged 18 years and over * Able to speak and understand English * Comfortable being randomised to either the open-label placebo or no-treatment control condition Exclusion Criteria: * Under 18 years of age * Unable to speak or understand English * Unable to provide informed consent

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Conditions

The condition(s) this trial relates to.

acute stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute stress Stress

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Canyon Swing

    Queenstown, Otago, 9300, New Zealand

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