New hope for hair loss: vitamin d cream vs steroid shots
NCT ID NCT07453238
First seen Jun 27, 2026 · Last updated Sep 21, 2026 · Updated 1 time
Summary
This study tests whether a vitamin D-based cream (calcipotriol) works as well as steroid injections for regrowing hair in people with patchy alopecia areata. Sixty adults with less than half their scalp affected will use one of the two treatments for 12 weeks. The goal is to see which option is more effective and safer for managing this autoimmune hair loss condition.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 50 years * Clinically diagnosed patchy alopecia areata * Scalp involvement of less than 50% (SALT score \<50%) * No topical or systemic treatment for alopecia areata within the previous 3 months * Willingness to provide written informed consent Exclusion Criteria: * Diffuse alopecia areata or scarring alopecia * Presence of other autoimmune diseases or significant systemic illness * Known hypersensitivity to calcipotriol or corticosteroids * Pregnant or lactating women * Current use of immunosuppressive therapy * Unwillingness to participate or provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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