Caffeine jolt may speed Kids' recovery from MRI sedation
NCT ID NCT06538584
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether giving caffeine to children after sedation for an MRI scan can help them wake up and recover faster. About 100 children aged 3 to 12 will receive either caffeine or a placebo shortly after their MRI. The goal is to see if caffeine reduces the time it takes for them to be ready for discharge, improving their experience and hospital efficiency.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- caffeine citrate
- What this could lead to
- If it works, this could offer a simple way to help children wake up faster and feel better sooner after sedation for MRI scans.
- What could go wrong
- This is a small, early pilot study, so results may not be conclusive. Caffeine might not speed recovery or could cause side effects like jitteriness or heart issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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3 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Undergo Magnetic Resonance Imaging (MRI) scan * Age ≥3 and ≤ 12 yr old * Both Male and Female * Weight ≤33.3 kg * American Society of Anesthesiologists ASA) physical status 1-3 * No History of Arrhythmia (3-leads Electrocardiogram \[EKG\] applied before and after the sedation) or congenital heart disease * Capable of obtaining consent from at least one parent * No history of liver and kidney impairment * No history of head trauma * No prior history of difficulty with anesthesia * No personal or family history of malignant hyperthermia Exclusion Criteria: * Age \<3 or \>12 * Weight \>33.3 kg * ASA physical status \> 3 * History Arrhythmia, congenital heart disease, liver, and kidney diseases * Prior difficulty with anesthesia * Personal or family history of malignant hyperthermia * Unable to obtain consent * History of head trauma * Female subjects who are pregnant
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States