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Caffeine before C-Section: a simple fix for a common danger?

NCT ID NCT07076654

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving women a 200 mg caffeine pill before spinal anesthesia for a planned C-section could prevent a dangerous drop in blood pressure. 90 full-term pregnant women took part. Half received caffeine, half a placebo. The main goal was to see how many women in each group developed low blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
caffeine (200 mg oral pill)
What this could lead to
If it works, this could offer a simple, low-cost way to prevent low blood pressure during C-sections, making the procedure safer for mothers.
What could go wrong
This is a small, single-center trial with only 90 participants. The results may not apply to all women, and caffeine can cause side effects like jitters or rapid heartbeat.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Jul 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * full term pregnant * undergoing elective cesarean delivery Exclusion Criteria: * patient refusal * baseline systolic pressure \< 100 mmHg * contraindication to spinal anesthesia * allergy to caffeine

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Caffeine Spinal hypotension

Contacts and locations

Locations

  • Cairo University

    Cairo, Cairo Governorate, 6890, Egypt

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