New drug aims to clear deadly protein buildup in organs

NCT ID NCT04512235

Ongoing Disease control Sponsor: Alexion Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding an investigational drug called CAEL-101 to standard treatment helps people with advanced AL amyloidosis live longer and spend less time in the hospital for heart problems. CAEL-101 is designed to help clear harmful protein deposits that build up in organs like the heart. The trial involves about 280 patients who have not yet received treatment for their condition.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Scottsdale, Arizona, 85259, United States
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Duarte, California, 91010, United States
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Palo Alto, California, 94304, United States
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San Francisco, California, 94143, United States
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Jacksonville, Florida, 32224, United States
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Weston, Florida, 33331, United States
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Indianapolis, Indiana, 46202, United States
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New Orleans, Louisiana, 70112, United States
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Baltimore, Maryland, 21201, United States
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Boston, Massachusetts, 02111, United States
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Boston, Massachusetts, 02118, United States
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Boston, Massachusetts, 02215, United States
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Detroit, Michigan, 48201, United States
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Rochester, Minnesota, 55905, United States
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St Louis, Missouri, 63110, United States
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New York, New York, 10032, United States
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New York, New York, 10065, United States
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Rochester, New York, 14642, United States
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Chapel Hill, North Carolina, 27599, United States
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Durham, North Carolina, 27705, United States
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Winston-Salem, North Carolina, 27157, United States
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Cleveland, Ohio, 44195, United States
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Columbus, Ohio, 43210, United States
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Portland, Oregon, 97239, United States
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Philadelphia, Pennsylvania, 19104, United States
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Nashville, Tennessee, 37232, United States
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Dallas, Texas, 75390, United States
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Houston, Texas, 77030, United States
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Salt Lake City, Utah, 84112, United States
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Seattle, Washington, 98109, United States
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Madison, Wisconsin, 53792, United States
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Milwaukee, Wisconsin, 53226, United States
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Box Hill, 3128, Australia
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Murdoch, WA6150, Australia
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Westmead, 2145, Australia
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Woolloongabba, 4102, Australia
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Linz, 4020, Austria
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Vienna, 1090, Austria
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Anderlecht, 1070, Belgium
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Leuven, 3000, Belgium
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Porto Alegre, 90110-270, Brazil
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Ribeirão Preto, 14051-140, Brazil
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Salvador, 41253-190, Brazil
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Calgary, Alberta, T2N 4N2, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Beijing, 100034, China
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Beijing, 100730, China
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Guangzhou, 510180, China
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Hangzhou, 310009, China
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Shanghai, 200032, China
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Suzhou, 215006, China
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Wenzhou, 325000, China
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Wuhan, 430022, China
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Ostrava Poruba, 708 52, Czechia
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Prague, 12808, Czechia
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Caen, 14033, France
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Créteil, 94000, France
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Dijon, 21079, France
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Lille, 59037, France
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Limoges, 87042, France
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Marseille, 13009, France
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Paris, 75010, France
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Pessac, 33604, France
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Pierre-Bénite, 69310, France
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Poitiers, 86021, France
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Rennes, 35033, France
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Toulouse, 31100, France
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Tours, 37044, France
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Berlin, 12203, Germany
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Düsseldorf, 40225, Germany
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Essen, 45147, Germany
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Hamburg, 22767, Germany
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Heidelberg, 69120, Germany
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Würzburg, 97080, Germany
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Athens, 11528, Greece
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Rio, 26504, Greece
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Thessaloniki, 54636, Greece
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Haifa, 31096, Israel
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Jerusalem, 91120, Israel
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Petah Tikva, 49100, Israel
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Tel Aviv, 64239, Israel
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Tel Litwinsky, 52621, Israel
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Brescia, 25123, Italy
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Fukushima, 960-1295, Japan
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Kanazawa, 920-8641, Japan
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Kashiwa-shi, 277-8567, Japan
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Kita-ku, 603-8151, Japan
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Kumamoto, 860-8556, Japan
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Matsumoto-shi, 390-8621, Japan
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Nagoya, 467-8602, Japan
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Shibuya-ku, 150-8935, Japan
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Gdansk, 80-214, Poland
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Warsaw, 01-748, Poland
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Saint Petersburg, 197022, Russia
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Seoul, 03722, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Barcelona, 08036, Spain
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Barcelona, 8035, Spain
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Gijón, 33394, Spain
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Granada, 18014, Spain
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Madrid, 28003, Spain
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Madrid, 28040, Spain
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Majadahonda, 28222, Spain
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Pamplona, 31008, Spain
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Salamanca, 37007, Spain
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Seville, 41013, Spain
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Valencia, 46009, Spain
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Glasgow, G12 0YN, United Kingdom
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London, NW1 2PG, United Kingdom

Conditions

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AL AMYLOIDOSIS