Engineered immune cells take on scleroderma in early trial
NCT ID NCT06328777
First seen Sep 30, 2025 · Last updated May 25, 2026 · Updated 21 times
Summary
This study tests a new treatment called CABA-201 for people with systemic sclerosis (scleroderma), a disease that causes hardening of the skin and can damage organs. The treatment uses a patient's own immune cells, modified to target and destroy certain immune cells that drive the disease. The trial aims to see if it is safe and can control the disease, but it is not expected to be a cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
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Mayo Clinic Florida
RECRUITINGJacksonville, Florida, 55905, United States
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Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Northwestern Memorial Hospital
RECRUITINGChicago, Illinois, 60611, United States
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The University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of Rochester
RECRUITINGRochester, New York, 14642, United States
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Yale University
RECRUITINGNew Haven, Connecticut, 06519, United States
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Conditions
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