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Tiny zaps to the heart could boost pumping power in advanced heart failure

NCT ID NCT04662034

First seen Jan 04, 2026 · Last updated May 24, 2026 · Updated 34 times

Summary

This study tested a small implanted device that sends very mild electrical currents to the heart muscle. It included 70 people with advanced heart failure (NYHA class III–IV) whose hearts were pumping at 25–35% of normal. The goal was to see if this microcurrent therapy, added to standard medications, could improve the heart's pumping strength over six months. The device was turned off at the end of the study.

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Contacts and locations

Locations

  • Bellvitge University Hospital

    Barcelona, Spain

  • Clinical Center of Serbia

    Belgrade, Serbia

  • Clinical Hospital Center Bezanijska Kosa

    Belgrade, Serbia

  • Clinical Hospital Dubrava

    Zagreb, 10000, Croatia

  • Diagnostic and Consultative Center Neoclinic Ead

    Sofia, 1408, Bulgaria

  • German Heart Center Charité

    Berlin, 13353, Germany

  • HNA Homolce Hospital

    Prague, Czech Republic, 15030, Czechia

  • Heart Center Dresden

    Dresden, Germany

  • Institute of Cardiovascular Diseases

    Kamenitz, 21204, Serbia

  • Institute of Cardiovascular Diseases Dedinje

    Belgrade, Serbia

  • Medical University Hannover

    Hanover, Germany

  • Polish-American Heart Clinic

    Bielsko-Biala, 43316, Poland

  • St. Luke´s Hospital

    Thessaloniki, Greece

  • Universitaetsspital Basel

    Basel, 4031, Switzerland

  • University Clinic

    Banja Luka, 78000, Bosnia and Herzegovina

  • University Clinic Sarajevo

    Sarajevo, 71000, Bosnia and Herzegovina

  • University Clinic Skopje

    Skopje, 1000, North Macedonia

  • University Hospital Regensburg

    Regensburg, Germany

  • University Hospital Wroclaw

    Wroclaw, Poland

  • Vivantes Humbold Clinic

    Berlin, 13509, Germany

Conditions

Explore the condition pages connected to this study.