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Can your immune system predict a c. diff relapse?

NCT ID NCT02440438

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how the immune system responds to Clostridium difficile infection in hospitalized patients. Researchers took blood samples every two days to measure immune markers. The goal was to find out why some patients have repeat infections. The study involved 56 participants and was completed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help identify which patients are at higher risk of relapse, leading to better monitoring or tailored treatments.
What could go wrong
This is an observational study with only 56 participants, so findings may not apply to all patients. Results are preliminary and need confirmation in larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Start date

Jan 2014

Finished

Aug 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Hospitalized * Suffering from diarrhea related to C. difficile * Confirmed diagnosis of CDI * Informed consent by the patient * Affiliated to the social security regime Exclusion Criteria: * Out-patient * No confirmed diagnosis of CDI * Decline of participation * Patient not affiliated to the social security regime

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Conditions

The condition(s) this trial relates to.

Clostridium difficile colitis Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diarrhea due to clostridium difficile

Contacts and locations

Locations

  • Service d'Hygiène, Epidémiologie et Prévention - Hôpital Edouard Herriot

    Lyon, 69437, France