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Brazilian flu vaccine shows promise in Head-to-Head trial

NCT ID NCT03777163

First seen May 17, 2026 · Last updated May 17, 2026

Summary

This study tested whether a new seasonal flu vaccine made by Butantan Institute works as well and is as safe as a standard Sanofi vaccine. 632 healthy adults in Brazil received one of the two shots. Researchers measured immune response and tracked side effects like pain, fever, and swelling for three weeks. The goal was to see if the Butantan vaccine is a good alternative for flu prevention.

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Contacts and locations

Locations

  • Centro de Pesquisas Clínicas do Instituto da Criança do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

    São Paulo, São Paulo, 05403 000, Brazil

  • Centro de Referência de Imunobiológicos Especiais (CRIE) Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

    São Paulo, São Paulo, 05403-000, Brazil

  • Centro de Referências para Imunobiológicos Especiais da Universidade Federal de São Paulo

    São Paulo, São Paulo, 01220200, Brazil

  • Unidade de Pesquisa Clínica do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo

    Ribeirão Preto, São Paulo, 14049900, Brazil

Conditions

Explore the condition pages connected to this study.