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Burst of hope: new brain zaps aim to silence chronic pain

NCT ID NCT05204472

First seen May 09, 2026 · Last updated Jun 23, 2026 · Updated 10 times

Summary

This study tests a new type of deep brain stimulation called Burst-DBS for people with long-term pain after a stroke or facial nerve injury. Twenty adults will have electrodes placed in the brain's thalamus and receive either burst or standard stimulation to see which reduces pain more. The goal is to find a better way to manage pain that hasn't responded to other treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dep. of Neurosurgery, Bern University Hospital

    RECRUITING

    Bern, 3000, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

burst deep brain stimulation (Burst-DBS) device

What this could lead to

If it works, this could offer a new way to ease chronic pain after stroke or facial nerve damage.

What could go wrong

This is a small, early feasibility trial with only 20 people. It may not show clear benefit, and brain surgery carries risks like infection or bleeding.

Conditions

The condition(s) this trial relates to.

neuralgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.