Could pepcid and a skin lotion finally stop burn scar itching?
NCT ID NCT06801626
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 29 times
Summary
This study tests whether a combination of famotidine (Pepcid) pills and cromolyn sodium lotion can reduce itching from burn scars. 44 adults with itchy burn scars will take either the active combo or a placebo (plus a standard antihistamine) for 6 months. The main goal is to see if itch severity drops, measured by a simple 0-10 scale.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Texas Medical Branch, Galveston
RECRUITINGGalveston, Texas, 77555, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Famotidine (Pepcid) and 4% cromolyn sodium lotion
What this could lead to
If it works, this could offer a new, effective way to reduce chronic itching from burn scars, improving quality of life.
What could go wrong
This is a small Phase 3 trial (44 people) and results may not apply to everyone. Itching is subjective, and the placebo group also gets an active antihistamine, so the added benefit of the study drugs may be modest.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.