Oral vs. needle: which stops Kids' seizures faster?
NCT ID NCT07626255
First seen Jun 08, 2026
Summary
This study tested whether giving midazolam in the mouth (buccal) works as well as a shot in the thigh (intramuscular) to stop seizures in children aged 6 months to 12 years. 90 children were randomly assigned to one of the two methods. The main goal was to see if seizures stopped within 5 minutes. The results could help make seizure treatment easier and less painful for kids.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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PAF Hospital Islamabad
Islamabad, Capital, 44000, Pakistan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
midazolam
What this could lead to
If buccal midazolam works as well or better than a shot, it could offer a simpler, less painful way to stop seizures in children.
What could go wrong
This is a small, single-hospital study (90 children) with a quasi-experimental design, so results may not apply broadly. The main risk is that seizures may not stop within 5 minutes with either method.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.