Oral vs. needle: which stops Kids' seizures faster?
NCT ID NCT07626255
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving midazolam in the mouth (buccal) works as well as a shot in the thigh (intramuscular) to stop seizures in children aged 6 months to 12 years. 90 children were randomly assigned to one of the two methods. The main goal was to see if seizures stopped within 5 minutes. The results could help make seizure treatment easier and less painful for kids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- midazolam
- What this could lead to
- If buccal midazolam works as well or better than a shot, it could offer a simpler, less painful way to stop seizures in children.
- What could go wrong
- This is a small, single-hospital study (90 children) with a quasi-experimental design, so results may not apply broadly. The main risk is that seizures may not stop within 5 minutes with either method.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
PAF Hospital Islamabad
Islamabad, Capital, 44000, Pakistan
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