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New drug aims to cut bleeding in knee replacements

NCT ID NCT07127042

First seen Jan 10, 2026 · Last updated May 23, 2026 · Updated 21 times

Summary

This study tests a new drug, BT-114143, to see if it can reduce blood loss during knee replacement surgery better than the current standard treatment. About 270 adults having knee replacement will receive either a high or low dose of BT-114143 or tranexamic acid. The main goal is to measure total blood loss around the time of surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Orthopaedics, West China Hospital, SIchuan University

    RECRUITING

    Chengdu, Si'Chuan, 37 Guoxuexiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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