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Nerve activity linked to jaw muscle stiffness in bruxism study

NCT ID NCT06824766

Knowledge-focused Sponsor: Bandırma Onyedi Eylül University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 89 people — some with bruxism (teeth grinding) and some healthy — to see if there is a connection between the body's 'automatic' nervous system and the tightness, stiffness, and elasticity of the chewing muscles. Participants wore a chest strap to measure heart activity and had their jaw muscles tested with a device. The goal was simply to understand these relationships better, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

89 people

The number who actually took part.

Started

Mar 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Bruxers

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with bruxism between the ages of 18-65, * A history of bruxism for at least 6 months, * Individuals with masseter muscle pain ≥4 at rest and during mastication * Control group: Healthy individuals aged 18-65 years Exclusion Criteria: * Masseter botox application in the last 6 months, * With regular use of analgesics and anti-inflammatories affecting the OSS, * Smokes 20 or more cigarettes daily, * With regular alcohol use of 1-2 glasses per day, * Daily coffee consumption of 6 cups or more, * Cardiovascular, respiratory and central nervous system diseases, * Presence of infection or tumoural structures within intraoral structures, * Multiple ear piercings, * With TMJ disc displacement and joint degeneration, * Cervical or TMJ fracture, systemic disease, musculoskeletal problem with evidence of specific pathological condition, * Any surgical operation related to cervical or TMJ problem, * Less than 6 months of cervical or TMJ-related physiotherapy and rehabilitation services, * The one with facial paralysis, * Diagnosed psychiatric illness * Participants who have communication difficulties in speaking and understanding Turkish or who are unable to understand the exercises

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Conditions

The condition(s) this trial relates to.

bruxism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bruxism

Contacts and locations

Locations

  • Bandırma Onyedi Eylül University

    Balıkesir, Turkey, 10200, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.