Tiny study on brown fat and cancer metabolism halted early
NCT ID NCT03621124
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study aimed to understand how brown adipose tissue (brown fat) might contribute to weight loss in cancer patients. Researchers planned to measure energy use in patients with and without active brown fat. However, the study was terminated early and only enrolled 3 participants, so no meaningful conclusions can be drawn.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What could go wrong
- The study was terminated early and only enrolled 3 people, so results are very limited and cannot be generalized.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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3 people
The number who actually took part.
- Started
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Aug 2018
- Finished
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May 2020
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients equal to or greater than forty years of age with an active cancer diagnosis.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ≥ 40 years of age * Have active cancer diagnosis. * Have had a PET/CT scan within the past 12 months at time of enrollment. * Ability to understand and the willingness to sign a written informed consent document Exclusion Criteria: * Current use of beta-blockers * Women who are pregnant or unsure of their pregnancy status * Women who are breastfeeding * Suffers from severe claustrophobia * Diagnosed with a serious psychiatric condition which could impede the judgement of the investigators, and/or the successful conduct of the recording. * In remission stage for cancer diagnosis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Virginia Commonwealth University/ Massey Cancer Center
Richmond, Virginia, 23298-0070, United States
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Other studies related to the condition(s) this trial covers.