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Can an extra inhaler boost lung clearance in cystic fibrosis patients on modern drugs?

NCT ID NCT05740618

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 26 times

Summary

This study looked at whether adding an inhaled sugar powder called Bronchitol (mannitol) can further improve mucus clearance from the lungs in 14 adults with cystic fibrosis who already take the triple-combination drug elexacaftor/tezacaftor/ivacaftor. Participants had moderate to severe lung disease. The goal was to see if the combination provides extra benefit or is redundant. Results may guide future use of these therapies.

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Contacts and locations

Locations

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

Conditions

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