Psoriasis drug safety under the microscope: brodalumab vs alternatives
NCT ID NCT03254667
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 32 times
Summary
This study tracks 3,500 adults with moderate-to-severe psoriasis to compare the long-term safety of brodalumab against other standard treatments. Participants are already taking these medications as part of their normal care. The main goal is to see if brodalumab is linked to a higher risk of cancer compared to other biologic drugs.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Registry
Bridgewater, New Jersey, 08807, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
brodalumab
What this could lead to
If successful, this study could provide real-world safety data to help doctors choose the best psoriasis treatment for their patients.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by factors like patient selection. It does not test a new treatment or aim for a cure.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.