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Broccoli sprout supplement may shield gut from alcohol damage

NCT ID NCT05902754

Disease control Sponsor: Louisiana State University Health Sciences Center in New Orleans Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a broccoli sprout extract supplement could improve gut health in older adults (50+) who drink at least 8 alcoholic drinks per week and have a low-quality diet. Over 28 days, 40 participants took either the supplement or a placebo. The goal was to see if the supplement could reduce gut leakiness and lower inflammation, which are linked to alcohol-related health problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
broccoli sprout extract (sulforaphane)
What this could lead to
If it works, this could point toward a simple dietary supplement to help protect the gut from damage caused by alcohol and poor nutrition.
What could go wrong
This was a small, early study with only 40 participants, so results may not apply to everyone. The supplement is generally safe, but it may not be strong enough to reverse long-term damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jan 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subjects ≥ 50 years of age at enrollment. * Consume at least 8 alcoholic drinks/week. AUDIT-C score \>8. Exclusion Criteria: * Bowel-related diseases * Diagnosed Diabetes * Allergy or intolerance to broccoli. * Any acute illness within the last 6 weeks. * Chronic anti-inflammatory use or antibiotic treatment in the last 7 days. * Acute illness within the preceding six weeks (defined as fever, new antibiotic use or unscheduled healthcare visit - for illness). * Acute alcohol intoxication upon arrival on the day of study visit. Additional exclusion criteria: • Any health issue that, the study investigator's judgement, confers excess risk for participation.

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Conditions

The condition(s) this trial relates to.

alcohol abuse Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol use disorder

Contacts and locations

Locations

  • Louisiana Health Sciences Center

    New Orleans, Louisiana, 70112, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.