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Could a quick digital test and blood draw detect Alzheimer's years early?

NCT ID NCT07284264

Diagnosis Sponsor: Xuanwu Hospital, Beijing Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This nationwide study in China aims to improve early detection of Alzheimer's disease. Researchers will screen 6,000 adults aged 50 and older using a digital cognitive test and a questionnaire, followed by blood tests to confirm Alzheimer's-related changes. The goal is to see if this stepwise approach is accurate and practical for community use.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple, widely available screening program for early Alzheimer's detection using digital tools and blood tests.
What could go wrong
This is an observational study, not a treatment trial. The screening methods may not be accurate enough for real-world use, and results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 6,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Jan 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Community residents aged 50 and above who have resided in the community for over one-year, self-report no cognitive impairment disorder or use of anti-dementia medications, and are capable of communicating in Chinese. Participants with a self-reported or clinically confirmed diagnosis of severe psychiatric disorders, such as bipolar disorder or schizophrenia, as well as those with medical conditions that impair their ability to complete cognitive assessments, were excluded.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. adults aged 50 and above; 2. living in community for at least one year and having established medical records; 3. denying a history of cognitive disorders (mild cognitive impairment, dementia, Alzheimer's disease, etc.) and the use of anti-dementia drugs (cholinesterase inhibitors or memantine, etc.); 4. agreeing to participate in the study; 5. individual or their relatives can communicate normally in Chinese. 6. high-risk groups for dementia（including:1. Complaints of cognitive decline and/or statements by the informant;2. History of AD in first-degree relatives;3. Known ApoE e4 carrier.） Exclusion Criteria: 1. Self-reporting or confirmation through inquiry indicates the presence of severe mental disorders, such as bipolar disorder or schizophrenia, etc. 2. Having a disease that makes it impossible to complete the cognitive assessment.

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Conditions

The condition(s) this trial relates to.

dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dementia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    6 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • General Hospital of Ningxia Medical University

    RECRUITING

    Ningxiang, China

  • Hainan Medical University

    RECRUITING

    Hainan, China

  • Shenzhen Center For Chronic Disease Control

    RECRUITING

    Shenzhen, China

  • The First Hospital of China Medical Unversity

    RECRUITING

    Shenyang, China

  • Xuanwu Hospital, Capital Medical University

    RECRUITING

    Beijing, China

  • Yichun People'S Hospital

    RECRUITING

    Yichun, China

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