Could a simple breathing workout boost heart failure Patients' stamina?
NCT ID NCT07672041
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new type of breathing muscle training for people with heart failure. 108 participants will either do the new breathing exercise, a standard one, or usual care for 8 weeks. Researchers will measure if it improves exercise capacity, breathing strength, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Inspiratory muscle training with tapered resistive load (POWERbreathe KH2 device)
- What this could lead to
- If successful, this could offer a more effective breathing exercise technique to help heart failure patients breathe easier, exercise more, and feel better day-to-day.
- What could go wrong
- This is an early-stage trial with only 108 participants, so results may not apply to all heart failure patients. The training requires consistent effort, and benefits may be modest or no better than standard breathing exercises.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 108 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * History of symptomatic heart failure (NYHA functional class I and III). * Participants able to understand and respond to the instructions given in the study * Participants with stable disease at the moment of inclusion in this study. * Unaltered dose and type of medication up to three months before the start of the study Exclusion Criteria: * Participants unable to perform a valid baseline cardiopulmonary exercise test. * Participants with unstable angina, acute myocardial infarction, and/or heart surgery within the past three months. * Participants with other concomitant cardiac or neurological disease. * Participants with difficulties in maintaining a proper mouth seal or unable to avoid air leakage during pulmonary function testing. * Participants in other non-pharmacological study will be also excluded. * Current smokers. * Cardiac acute decompensation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centro de Salud Sports Medicina Deportiva
Viña del Mar, Valparaiso, 2372067, Chile
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