New combo therapy aims to ease long COVID breathing troubles
NCT ID NCT07621588
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small pilot study tests whether adding mild electrical stimulation to simple breathing exercises can improve breathing, reduce fatigue, and boost quality of life in people with Long COVID. Ten adults aged 18-65 with a Long COVID diagnosis will be split into two groups: one does only breathing exercises, the other adds electrical stimulation to the diaphragm. The treatment lasts three weeks, with two sessions per week.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men and women aged 18 to 65 years. * Medical diagnosis of Long COVID. * At least 2 months since SARS-CoV-2 infection. * Ability and willingness to provide informed consent. * Ability to participate in the assigned intervention and assessment procedures. Exclusion Criteria: * Presence of a pacemaker. * History of epilepsy. * Pregnancy. * History of acute cardiac arrest. * Severe respiratory distress. * Use of a wheelchair. * Blurred vision. * Cyanosis. * Refusal to perform part or all of the treatment. * Incomplete or incorrectly completed questionnaires.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Clínica Universitaria Salus Infirmorum, Universidad Pontificia de Salamanca
Madrid, Madrid, 28015, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a home exercise program help long COVID patients take back control?
- Can slow breathing retrain the nervous system to fight long COVID?
- Can an arthritis drug clear long COVID brain fog?
- Can a brain zapping headset restore focus after long COVID?
- Mindfulness may offer relief for long COVID sufferers
- Can wearables decode the mystery of fatigue?