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Scientists dig into past breast sarcoma cases to find better ways to treat this rare cancer

NCT ID NCT04749446

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study reviews medical records of 300 people diagnosed with breast sarcoma between 2000 and 2020. Researchers will analyze symptoms, treatments, and outcomes to identify patterns that could guide future care. Because it is a retrospective study, it does not test a new treatment but aims to gather knowledge.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better understand breast sarcoma and suggest more effective treatment approaches.
What could go wrong
This is a retrospective study that only looks at past data, so it cannot prove that any treatment works. The results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2021

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients affected by breast sarcma referred to participating Institutions between January 2000 and June 2020.

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \>18 years at diagnosis * primary or secondary breast sarcoma * availability of medical data needed for the study (histopathological data, surgery, chemotherapy, including preceding chemotherapeutic regimens for secondary breast sarcomas, radiation therapy) Exclusion Criteria: * sarcoma metastases to the breast * chest wall sarcomas not arising in the mammary gland * cutaneous sarcomas

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    14 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • A.O Ospedali Riuniti Marche Nord

    NOT_YET_RECRUITING

    Ancona, Italy

  • ASL Città di Torino (Dipartimento di Oncologia)

    NOT_YET_RECRUITING

    Torino, 10153, Italy

  • Azienda Ospedaliera S. Orsola-Malpighi

    NOT_YET_RECRUITING

    Bologna, BO, 40138, Italy

  • Azienda Ospedaliera Universitaria Careggi

    NOT_YET_RECRUITING

    Florence, 50100, Italy

  • Azienda Ospedaliera Universitaria Paolo Giaccone

    NOT_YET_RECRUITING

    Palermo, PA, 90127, Italy

  • Centro di Riferimento Oncologico - Unit of Medical Oncology

    NOT_YET_RECRUITING

    Aviano, Pordenone, 33081, Italy

  • Fondazione IRCCS INT Milano

    NOT_YET_RECRUITING

    Milan, 20133, Italy

  • Fondazione del Piemonte per l'Oncologia IRCC Candiolo

    RECRUITING

    Candiolo, Torino, 10060, Italy

  • Istituto Clinico Humanitas

    NOT_YET_RECRUITING

    Rozzano, MI, 20089, Italy

  • Istituto Europeo di Oncologia

    NOT_YET_RECRUITING

    Milan, MI, 20141, Italy

  • Istituto Nazionale Tumori Regina Elena - Unit of Medical Oncology I

    NOT_YET_RECRUITING

    Roma, 00144, Italy

  • Ospedale Misericordia e Dolce

    NOT_YET_RECRUITING

    Prato, PO, 59100, Italy

  • Ospedale Umberto I

    NOT_YET_RECRUITING

    Turin, TO, Italy

  • Policlinico Universitario Campus Biomedico

    NOT_YET_RECRUITING

    Roma, RM, 00128, Italy