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Can a second nerve block cut opioid use after breast reduction?

NCT ID NCT07432256

Symptom relief Sponsor: Zonguldak Bulent Ecevit University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether adding a nerve block near the breastbone to a standard chest wall block could reduce painkiller use after breast reduction surgery. 90 women were split into three groups: one got no nerve block, one got a standard block, and one got both blocks. Researchers measured how much opioid pain medication they needed in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
local anesthetic (nerve block injection)
What this could lead to
If adding the extra nerve block works, it could give surgeons a better way to control pain after breast reduction and reduce the need for strong painkillers.
What could go wrong
This is a small, completed study with 90 people, so results may not apply to everyone. The extra block might not provide meaningful additional pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

May 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18-65 years * Scheduled for elective breast reduction surgery under general anesthesia * American Society of Anesthesiologists (ASA) physical status I-III * Ability to understand the study and provide written informed consent Exclusion Criteria: * Patient refusal * Known allergy to local anesthetics * Coagulopathy or ongoing anticoagulant therapy * Infection at the block site * Chronic opioid use or opioid dependence * Severe hepatic or renal insufficiency * Pregnancy or breastfeeding

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Conditions

The condition(s) this trial relates to.

agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast reduction Opioid consumption Postoperative pain

Contacts and locations

Locations

  • Zonguldak Bulent Ecevit University Hospital

    Zonguldak, Maltepe, Turkey (Türkiye)

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