New MRI scan spots hidden fat clues to breast cancer
NCT ID NCT03400215
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new, 15-minute MRI scan that measures the types of fat in breast tissue. Researchers want to see if women with breast cancer have more saturated fat in their breasts than women with benign lumps. About 190 postmenopausal women will get the extra scan during their regular breast MRI. If the method works, it could offer a new, non-invasive way to assess breast cancer risk.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Gradient-echo Spectroscopic Imaging (GSI) MRI scan
- What this could lead to
- If successful, this could lead to a non-invasive way to assess breast cancer risk by measuring breast fat composition during a routine MRI.
- What could go wrong
- This is an observational study, not a treatment trial. The results may not lead to a direct clinical test, and the link between breast fat and cancer risk is still unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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190 people
The number who actually took part.
- Started
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Jul 2018
- Expected to finish
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Apr 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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25 to 99 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * No contraindications to MRI scanning (pacemaker, implanted metallic objects, severe obesity or other condition that leads to difficulty lying in the magnet) * No contraindication to gadolinium contrast agent (severe renal insufficiency (EGFR\<30), allergy to gadolinium) which will be injected for clinical exam * Able and willing to provide informed consent * Post-menopausal age \> 25 years. Exclusion Criteria: * Contra-indication to MRI or gadolinium contrast agent (have a pacemaker, aneurysm clip, or other metallic implant; weigh \>135 kg; or have renal impairment) * Breast surgery within prior 12 months, or breast implants * Any hormonal therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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NYU Langone Health
New York, New York, 10016, United States
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