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Could fewer radiation doses be just as good for breast cancer?

NCT ID NCT02276885

Symptom relief Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if a shorter course of radiation (3 doses over 5 days) is as safe and works as well as the standard 5-dose schedule for women with early-stage breast cancer. About 284 post-menopausal women with small, low-risk tumors took part. The main goal is to see if the shorter treatment causes less scarring (fibrosis) while still preventing cancer from coming back.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

284 people

The number who actually took part.

Started

Oct 2014

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 90 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Post-menopausal women defined as either: 1. at least 2 years without menstrual period 2. patients older than 50 with serological evidence of post-menopausal status 3. hysterectomized patients of any age with FSH confirmation of post- menopausal status * pT1 breast cancer, excised with negative margins. Criteria for low risk-pTis: 1. Screen-detected 2. Low to intermediate nuclear grade 3. \< 2.5cm in size 4. Resected with negative margins at \>3mm) * clinically N0 or pN0 or sentinel node negative breast cancer Exclusion Criteria: * previous radiation therapy to the ipsilateral breast * presence of a proportion of DCIS in the core biopsy specimen which is compatible with extensive intraductal component (EIC)

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer

Contacts and locations

Locations

  • NYU Langone Medical Center

    New York, New York, 10016, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.