New model may help predict survival in breast cancer patients with brain lining spread
NCT ID NCT07386886
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 403 breast cancer patients whose cancer had spread to the lining of the brain and spinal cord. Researchers collected detailed medical information to understand what factors affect survival. They used this data to create a new scoring system that could help doctors predict how long patients might live and guide treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a better way to predict outcomes for breast cancer patients with leptomeningeal metastasis, helping doctors tailor treatment.
- What could go wrong
- This is an observational study, not a treatment trial. The new model needs further testing in other groups before it can be widely used.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
403 people
The number who actually took part.
- Started
-
Nov 2013
- Finished
-
Jan 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The investigators conducted a large, multicenter retrospective study of patients with breast cancer leptomeningeal metastasis (BCLM), constituting one of the largest and most comprehensively curated cohorts to date. Data from 403 patients diagnosed between November 2013 and November 2025 were collected from three major academic centers.
- Ages
-
18 to 80 years
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients with BCLM Exclusion Criteria: * patients with other BC CNS metastasis
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Leptomeningeal metastasis in breast cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.