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Screening vs. symptoms: which breast cancer detection leads to better life after treatment?

NCT ID NCT03877029

Knowledge-focused Sponsor: Norwegian Institute of Public Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at over 4,400 women to compare long-term quality of life between those whose breast cancer was found through screening and those whose cancer was found through symptoms. Researchers measured quality of life at different times after diagnosis and also compared results to women who had screening but never had breast cancer. The goal is to understand how the way cancer is found affects side effects and overall well-being after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors understand whether finding breast cancer through screening leads to better quality of life after treatment compared to finding it through symptoms.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly change patient care. Results may show differences but cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

4,487 people

The number who actually took part.

Started

Nov 2019

Finished

Dec 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will include women residing in Norway, who are currently alive and were invited and attended, and were invited but did not attend the screening program. Among the attending and not attending women, women who were diagnosed with breast cancer 2006-2017 will be randomly selected. The women diagnosed with breast cancer will be stratified by detection mode (screen-detected versus symptomatic breast cancer). The women within each group will be matched by age. Additionally, women who have never had a diagnosis of breast cancer will be randomly selected from the target population of BreastScreen Norway.

Ages

50 to 69 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Study II Inclusion Criteria: * Screened in BreastScreen Norway and diagnosed with breast cancer between 2006 and 2017 * Diagnosed with symptomatic breast cancer between 2006 and 2017 and never attended screening * Screened in BreastScreen Norway and diagnosed with interval breast cancer between 2006 and 2017 * Screened in BreastScreen Norway and have never been diagnosed with breast cancer Exclusion Criteria: * Death after recruitment Study III Inclusion Criteria: * Screened in BreastScreen Norway and diagnosed with breast cancer between 2006 and 2017 * Screened in BreastScreen Norway and diagnosed with interval breast cancer between 2006 and 2017 * Diagnosed with symptomatic breast cancer between 2006 and 2017 and never attended screening Exclusion Criteria: * Death after recruitment

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer

Contacts and locations

Locations

  • Cancer Registry of Norway

    Oslo, Oslo, 0304, Norway

More trials for these conditions

Other studies related to the condition(s) this trial covers.