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Gene test may predict how breast cancer responds to hormone therapy

NCT ID NCT06127979

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 23 times

Summary

This study looks at how a marker called Ki67 changes in breast cancer cells after hormone therapy in people with and without a BRCA2 gene mutation. About 42 postmenopausal women with ER+/HER2- breast cancer will take hormone therapy before surgery. Researchers want to see if the BRCA2 mutation affects how much Ki67 drops, which may help guide future treatment decisions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.