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Can brain scans predict suicide risk in youth? new study tests Therapy's brain impact

NCT ID NCT07568054

First seen May 06, 2026 · Last updated Jun 21, 2026 · Updated 12 times

Summary

This study uses brain imaging to explore why some young people have suicidal thoughts or attempt suicide. Researchers will scan the brains of 60 participants aged 14-24, including those recently hospitalized after a suicide attempt, those with chronic suicidal thoughts, and healthy controls. High-risk participants will receive a specialized talk therapy called CAMS, and their brains will be scanned again to see if the therapy changes brain activity. The goal is to find biological markers that could help predict suicide risk and guide more effective treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Cleveland Clinic

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Collaborative Assessment and Management of Suicidality (CAMS) therapy

What this could lead to

If successful, this could lead to better ways to predict suicide risk in young people and show how a specific therapy changes the brain to reduce suicidal thoughts.

What could go wrong

This is an early-stage observational study with only 60 participants, so results may not apply to everyone. It looks at brain changes, not whether the therapy prevents suicide long-term.

Conditions

The condition(s) this trial relates to.

Depression major depressive disorder Suicidal Ideation Suicide, Attempted

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.