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Scientists map how healthy brains block out bad memories

NCT ID NCT06891612

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at how healthy young adults (ages 18-35) suppress negative emotional memories. Researchers used EEG to track brain activity while participants performed memory-suppression tasks. The goal was to better understand the brain's natural ability to forget unpleasant experiences, which could help explain why this process goes wrong in conditions like anxiety and depression.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help explain how the brain blocks out bad memories, potentially pointing toward new ways to treat anxiety or depression.
What could go wrong
This is a small, completed observational study in healthy people, not a treatment trial. The findings may not apply to people with mental health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

78 people

The number who actually took part.

Started

Jun 2016

Finished

Apr 2019

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female aged between 18 and 35 years * Affiliated to a social security scheme * Having French as their mother tongue * Right-handed * High school graduate or equivalent * Having signed a written informed consent Exclusion Criteria: * Pregnancy in progress, pregnancy test will be performed * Person deprived of liberty by judicial or administrative decision * Person hospitalized without consent and not subject to legal protection measures, and person admitted to a health or social care facility for purposes other than research * Minor * Adults subject to legal protection measure (guardianship, curatorship or judicial protection), adults unable to express their consent and not subject to protection measure * Person subject to an exclusion for another research * History of a neurological, psychiatric disorders, or head trauma with loss of consciousness for more than an hour * History of cancer over the last 5 years, with the exception of squamous cell carcinomas of the skin * Presence or history of chronic alcoholism or drug addiction * Taking medications that may alter cognitive and/or brain function (decision of the principal investigator) * Presence of visual and/or auditory disorders sufficiently significant to affect the progress of the tests * Contraindications to electroencephalography * Presentation of unpleasant images that are too emotionally disturbing for the participant (by decision of the physician)

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety Cognitive control Depression

Contacts and locations

Locations

  • Service de neurologie CHU de Caen

    Caen, 140330 Caen Cedex 9, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.