Brain zaps timed to your own rhythms may boost Hand-Eye control
NCT ID NCT07249801
First seen Jun 24, 2026 · Last updated Sep 16, 2026 · Updated 3 times
Summary
This pilot study tests whether personalized brain stimulation can improve hand-eye coordination in people with brain lesions. Researchers will use a technique called repetitive transcranial magnetic stimulation (rTMS) timed to each person's natural brain rhythms. Twenty adults with upper limb sensorimotor impairment will participate, and the study will measure changes in grip force precision and brain connectivity.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- repetitive transcranial magnetic stimulation (rTMS)
- What this could lead to
- If successful, this could point toward a personalized brain stimulation technique to improve hand-eye coordination after brain injury.
- What could go wrong
- This is a very early, small pilot study with only 20 participants. It is designed to test feasibility and measure brain changes, not to prove a treatment works. Results may not lead to a practical therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * adult volunteers (age ≥18 years) * right-hand dominance (defined with the Edinburg Handedness Scale) * voluntary whole-hand grip force (Medical Research Council scale for muscle force ≥2) * capable of repeated grasp and release with 5% of maximum voluntary contraction (standardized with an in-house computer-based assessment involving whole-hand grip force tracking upon visual cues with a digital dynamometer). Exclusion Criteria: * presence of any MRI risk factors (such as an electrically, magnetically, mechanically activated metal or nonmetal implant including cardiac pacemaker, intracerebral vascular clips, any other electrically sensitive support system, or claustrophobia) * presence of any contraindications to repetitive transcranial magnetic stimulation, rTMS (e.g., history of seizures or epileptic activity, currently taking medications that lower seizure thresholds) * any neurological or psychiatric disorders affecting cognitive function (e.g., established dementia) affecting the ability to understand the purpose of the study and give informed consent or ability to complete cognitive testing * substance use disorder * visual impairment that precludes completion of scanner tasks * uncontrolled hypertension despite treatment * intake of tricyclic anti-depressants * musculoskeletal disorders affecting bimanual grasp- and release * pregnancy (or suspected/possible pregnancy or plan to become pregnant in the short term). If the participant is a woman of childbearing potential, a urine pregnancy test will be performed on a standard basis. * severe aphasia affecting particularly of receptive nature (NIH Stroke Scale, NIHSS Language subsection ≥2) affecting the ability to understand the purpose of the study and give informed consent * pregnancy
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States