Light and zaps: new combo therapy shows promise for memory loss
NCT ID NCT07290686
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new, drug-free approach to help older adults with mild cognitive impairment or Alzheimer's disease. The method combined gentle electrical brain stimulation, cognitive training, and near-infrared light therapy delivered through the nose. The goal was to see if this combination could improve thinking, memory, and quality of life. The study involved 33 participants and measured changes in cognitive test scores right after treatment and again 12 weeks later.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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33 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Apr 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * diagnosis of MCI/AD * MMSE 12-26 points * ADAS- COG \> 17 points * signed inform consent form * minimum 8 years of education * stable drug doses for minimum 3 months Exclusion Criteria: * diagnosis of mental disability, schizophrenia, bipolar disorder, depression, alcohol and/or drug addiction, * unstable somatic state * lack of signed inform consent form
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Old Age Psychiatry and Psychotic Disorders Medical University of Lodz
Lodz, Łódź Voivodeship, 92-213, Poland
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Other studies related to the condition(s) this trial covers.
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