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Could a gentle brain zap help kids with cerebral palsy move better?

NCT ID NCT07574996

Disease control Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will test whether a gentle brain stimulation technique called tDCS, combined with task-oriented training and virtual reality, can improve movement and brain activity in 150 children with spastic cerebral palsy. Participants will be randomly assigned to receive either real or sham stimulation alongside therapy. The goal is to see if this combination leads to better motor skills, balance, and brain function compared to standard physiotherapy alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS) combined with task-oriented training and virtual reality
What this could lead to
If successful, this could point toward a new, non-invasive way to improve motor function and brain activity in children with cerebral palsy, potentially reducing disability.
What could go wrong
This is an early-stage trial with no phase designation, so results are uncertain. The intervention is complex and may not show clear benefits over standard therapy. Risks include possible discomfort from stimulation, though it is considered safe at low intensities.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children aged 6-18 years. * Neurologist-confirmed spastic cerebral palsy. * GMFCS Levels I-III (mild to moderate motor impairment). * Ability to understand and follow simple instructions. * Medically stable (no planned major surgery; no recent adjustment of medications affecting cortical excitability). * Parental/guardian written informed consent and child assent. Exclusion Criteria: * Active uncontrolled epilepsy or history of seizure in the last year. * Metal implants in the head or implanted medical/electrical devices (e.g., cochlear implants, ventriculoperitoneal shunts, pacemakers). * Significant visual or auditory impairments that would interfere with task performance. * Severe behavioral or cognitive difficulties that would prevent safe application of tDCS or training tasks. * Currently taking medications known to significantly alter cortical excitability (e.g., benzodiazepines, antiepileptics) if dosage is unstable. * Participation in other experimental neurorehabilitation or brain stimulation interventions within the last 6 months.

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Conditions

The condition(s) this trial relates to.

cerebral palsy spastic cerebral palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral palsy

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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