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Can zapping the brain reveal the secrets of how we choose?

NCT ID NCT07749378

Knowledge-focused Sponsor: Wuerzburg University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study asks whether two brain regions—the striatum and the hippocampus—support different decision-making strategies. Healthy young adults will choose between objects while receiving non-invasive electrical stimulation to one of these regions or a sham control. The researchers will see if stimulating the striatum boosts reliance on learned reward associations, while hippocampal stimulation enhances generalization to related objects. The findings could illuminate the neural basis of flexible decision-making.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transcranial temporal interference stimulation (tTIS) targeting the hippocampus or striatum
What this could lead to
If successful, this could clarify how the brain balances different decision-making strategies, potentially informing future treatments for decision-making disorders.
What could go wrong
This is a small, early-stage study in healthy volunteers, so results may not apply to broader populations. The stimulation is non-invasive but may have mild side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 36 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * No diagnosis of any neurological or psychiatric disease Exclusion Criteria: * Severe neuropsychiatric or unstable systemic disease * Severe sensory or cognitive impairment or musculoskeletal dysfunction that would prevent subjects from understanding the task instructions or executing the tasks * Implanted medical devices * Diagnosis of epilepsy or history of one or more epileptic seizure(s) * Pieces of metal in/around the head * Regular consumption of narcotics (also excluded: cannabis within past month, alcohol abuse or dependence) * Pregnancy and breast feeding * Incapability of giving informed consent * Left-handedness Subjects included in the study will be excluded from analyses if their datasets are incomplete. To ensure full counterbalancing, excluded subjects will be replaced by new ones.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Young healthy adults

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Hospital Würzburg (UKW)

    RECRUITING

    Würzburg, Bavaria, 97080, Germany

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