Could zapping the brain and spine together boost recovery?
NCT ID NCT07334977
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether combining non-invasive brain and spinal cord stimulation during a movement task can improve hand function and thinking in people with stroke or spinal cord injury. 45 participants will receive both types of stimulation separately and together to see if they work better as a pair. The goal is to understand how these techniques might help recovery, not to provide a treatment yet.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- tDCS (transcranial Direct Current Stimulation) and tSCS (transcutaneous Spinal Cord Stimulation)
- What this could lead to
- If successful, this could point toward a new rehabilitation approach that combines brain and spinal stimulation to improve recovery after neurological injuries.
- What could go wrong
- This is a small early-phase study (45 people) testing immediate effects only. It may not translate to long-term benefits or work for all types of injuries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: CONTROL GROUP: * Over 18 years of age * Participant who has signed an informed consent form * Participant who is affiliated with and covered by the social security system POST-STROKE GROUP: * Over 18 years of age * Who sustained a stroke more than 3 weeks ago * Considered medically stable by the medical investigator * Who has signed an informed consent form * Affiliated with and covered by the social security system SCI GROUP: * Over 18 years of age * Considered to have a complete or incomplete spinal cord injury (i.e., with a score on the Spinal Injury Association (ASIA) Impairment Scale (AIS) score from A to D) * Considered medically stable by the investigating physician * Presenting with quadriplegia due to cervical injury * Who has signed an informed consent form * Affiliated with and covered by the social security system. Exclusion Criteria: * Suffering from a chronic condition * Skin problems or open wounds * History of epilepsy or seizures * Presence of a contraindication to the use of magnetic/electrical stimulation or MRI, including: cardiac pacemaker; implanted hearing aid; intraocular foreign body, shrapnel, or bullets; metal worker; pacemaker or neurostimulator; claustrophobia * Presence of implanted medical devices (cardiac valve, endovascular devices, ventricular shunt valve, surgical clips, metallic sutures, staples, stent, osteosynthesis or arthrodesis hardware) not classified as "MR Conditional" according to ASTM F2503. * Individuals who are legally incompetent, under judicial protection, guardianship, or trusteeship * Pregnant and/or breastfeeding women * Individuals who refuse to be informed of any abnormalities that may be detected by MRI.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre de la Tour de Gassies
RECRUITINGBruges, 33520, France
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Service de Médecine Physique & Réadaptation - CHU Bordeaux
RECRUITINGBordeaux, 33000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Heart hole or stroke trigger? global registry tracks who gets closure and what happens next
- Zapping the spine while wearing a robotic ankle: a new way to help kids walk?
- Can a nurse and a neighbor help tame chronic disease?
- Can PET scans reveal hidden heart inflammation after a stroke?
- Two ways to catch a hidden heart rhythm after stroke