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Brain scans reveal why we drink despite Tomorrow's To-Do list

NCT ID NCT04895033

Knowledge-focused Sponsor: University of Kansas Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study used brain scans (fMRI) to see what happens in the brain when heavy drinkers decide whether to drink alcohol, especially when they have important plans the next day. 52 heavy drinkers took part. The goal was to understand how the brain weighs the choice to drink against responsibilities, and how alcohol problems relate to these decisions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

52 people

The number who actually took part.

Started

Feb 2023

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. 21-55 years of age; 2. current heavy alcohol drinking in the past three months, as indicated by reporting consumption of 14 or more drinks per week for men or 7 or more drinks per week for women and at least one heavy drinking episode weekly (5+/4+ drinks in a single occasion for males/females); 3. belong to a category with significant responsibilities, such as being currently employed, a current student, or a caregiver with significant responsibilities; 4. speak English; 5. normal or corrected to normal vision and hearing; 6. able to give informed consent. Exclusion Criteria: 1. currently engaged in treatment or seeking treatment for alcohol-related problems; 2. major psychiatric illness (psychotic disorder, bipolar disorder, post-traumatic stress disorder); 3. Diagnostic and Statistical Manual Version-5 substance use disorder (except nicotine); 4. attending any in-person session with a positive breath alcohol concentration (BrAC \> 0.00%); 5. any contraindications for MRI scanning (e.g., metal in body surgically or accidentally including pacemaker, cochlear implants, aneurysm clips, shrapnel, etc.); 6. history of seizures or anti-seizure medication; 7. history of concussion or other significant brain injury; 8. serious medical illness unsuitable for the MRI scanner based on best clinical judgment

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Conditions

The condition(s) this trial relates to.

Alcohol Drinking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol drinking

Contacts and locations

Locations

  • Cofrin Logan Center for Addiction Research and Treatment

    Lawrence, Kansas, 66045, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.