Brain waves may predict hearing implant success
NCT ID NCT07500909
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how brain processes like attention and inhibition help people adapt after hearing loss. Researchers will use EEG to measure brain waves in 90 adults receiving cochlear implants, comparing them to normal-hearing participants. The goal is to find brain markers that predict how well someone will recover hearing ability.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants with cochlear implants will be informed about this study during a routine check-up at the partner hearing aid laboratory (Audial), or by the ENT department at Purpan Hospital during a consultation as part of patient follow-up. All participants with normal hearing (young and old) will be recruited through announcements made to members of the ENT department and the CerCo UMR 5549 laboratory.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: For cochlear implant patients: * Adult patients * Profound bilateral hearing loss requiring a first cochlear implant * Normal cochlear anatomy (confirmed by preoperative imaging) * Full insertion of the cochlear electrode array planned * Acceptance of the protocol and signing of the informed consent form * Enrollment in a social security or equivalent plan For young patients with normal hearing: * Adult patients aged 18 to 40 * Normal and symmetrical hearing * Acceptance of the protocol and signature of the informed consent form * Affiliation with a social security scheme or equivalent For older patients with normal hearing: * Patients over 50 years of age, matched by gender and age (+/- 2 years) with the cochlear implant patient group * Normal and symmetrical hearing, with hearing thresholds \< 20 dB HL at 2 kHz and \< 40 dB HL at 4 kHz * Acceptance of the protocol and signature of the informed consent form * Affiliation with a social security scheme or equivalent For experienced cochlear implant recipients: * Adult patients. * Unilateral cochlear implant activated for 1 year or more. * Disyllabic word recognition score at 60 dB in free field of 70% or higher. * Acceptance of the protocol and signature of the informed consent form. * Affiliation with a social security plan or equivalent. For severely deaf patients fitted with hearing aids: * Adult patients. * Severe bilateral hearing loss. * Rehabilitation with one or two optimally fitted hearing aids. * Acceptance of the protocol and signing of the informed consent form. * Enrollment in a social security or equivalent health insurance plan. Exclusion Criteria: * History of associated neurological pathology * Etiologies with unfavorable prognoses, such as recurrent chronic otitis media: These conditions are associated with a poor prognosis due to chronic inflammation that can affect the cochlea * Duration of profound bilateral deafness exceeding 5 years (worse prognosis) * Contraindications to EEG or other neurophysiological examinations within the study (for all groups) * Cognitive impairment confirmed by the MOCA test for the cochlear implant patient group and the group of elderly subjects with normal hearing * Use of psychotropic medications that may interfere with the results of cognitive or neurological tests * History of epilepsy or other major neurological disorders * Pregnancy or breastfeeding * Participation in another interventional research protocol or one that impacts the criteria studied in this project * Individuals under legal guardianship (guardianship, tutorship, curatorship, institutionalized, or under a future protection mandate)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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