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Study reveals how exercise impacts oxygen in COPD brains and muscles

NCT ID NCT07285642

Knowledge-focused Sponsor: Saglik Bilimleri Universitesi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how walking, strength training, and breathing exercises change oxygen levels in the brain and leg muscles of people with moderate-to-severe COPD. Researchers will compare 60 participants (30 with COPD and 30 healthy adults) using special light-based sensors. The goal is to learn which exercises are safest and most effective for COPD patients, helping to create better rehabilitation programs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help design safer, personalized exercise programs for people with COPD that avoid dangerous drops in oxygen.
What could go wrong
This is a small, early-stage study focused on measuring oxygen changes, not testing a treatment. Results may not apply to all COPD patients or lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Age 40-70 years * Diagnosis of moderate-to-severe COPD (GOLD stage II-III) * Stable disease (no exacerbation in previous 4 weeks) * BMI 18.5-24.9 kg/m² * Manual muscle strength ≥ 4 (MRC scale) * Ability to perform exercise tests safely * Written informed consent Exclusion Criteria * Severe comorbid conditions (uncontrolled cardiac, neurological, or orthopedic disease) * Need for high-flow oxygen therapy (\>2 L/min) * History of cerebrovascular disease or transient ischemic attack * Musculoskeletal or dermatological conditions impairing NIRS measurement sites * Restrictive lung disease, interstitial lung disease, or small-airway disease * Participation in an exercise program within the last 12 months Healthy Controls * Age 40-70 years * No acute or chronic disease * Non-smoker * BMI 18.5-24.9 kg/m² * No musculoskeletal limitations

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Esra Pehlivan

    RECRUITING

    Istanbul, 34668, Turkey (Türkiye)

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